Bio Devices | Foundry Services | SCIVAX
Foundry Application

Bio Devices

We support mass production of advanced bio devices such as NGS, microfluidics, and OOC. Specialist staff with deep knowledge of bio-specific challenges, including biotoxicity and autofluorescence, bridge nanotechnology and biotechnology.

Bio Devices
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Why Choose SCIVAX
01

Extensive Mass-Production Experience

Leveraging mass-production experience with NGS-related products, we propose materials and processes from the prototyping stage with future mass production in mind.

02

Support for Both UV and Thermal Molding

We offer a variety of processes and molding materials, including not only UV nanoimprint but also thermal molding. The optimal process can be selected according to the application.

03

Integrated Supply Chain

We have established a supply chain covering mold design, mold fabrication, prototype molding, substrate procurement, and dicing.

04

Molding in an ISO Class 5 Clean Environment

After the full molding process in a Class 100 (ISO Class 5) cleanroom, dicing, ID marking, and quality inspection are performed at the post-process facility before shipment.

05

Support from Bio Specialists

Specialists in the bio field bridge biotechnology and nanotechnology. They address bio-specific challenges such as biotoxicity and autofluorescence, significantly shortening development time.

06

World-First PMF Development and Mass-Production Support

We developed the world’s first PMF (Porous Membrane Film), a through-hole film made using nanoimprint technology. It supports a wide range of bio applications including OOC (Organ-on-Chip).

World First

PMF (Porous Membrane Film) — Through-Hole Film by Nanoimprint

We developed the world’s first PMF (Porous Membrane Film), a through-hole film made using nanoimprint technology. It supports a wide range of bio applications including OOC (Organ-on-Chip).

Specifications
ItemSpecifications / Supported Range
Supported DevicesNGS chips (flow cells), OOC, PMF (porous membrane films)
Molding ProcessUV nanoimprint / thermal molding
CleanroomISO Class 5(Class 100)
Post-ProcessingDicing, ID marking, quality inspection
Material SupportMaterial selection considering biotoxicity and autofluorescence
Scope of SupportIntegrated support from mold design to prototyping and mass production
Example Process
Glass Substrate
Step 1
Glass Substrate
Hydrophobic Surface Treatment
Step 2
Hydrophobic Surface Treatment
e.g. HMDS
Nanoimprint Resin Coating
Step 3
Nanoimprint Resin Coating
Nanoimprint
Step 4
Nanoimprint
Ashing and residual layer/HMDS removal
Step 5
Residual layer and HMDS removal by ashing
Hydrophilic Treatment
Step 6
Hydrophilic Treatment
e.g. γAPTES
Lift-off treatment of nanoimprint resin
Step 7
Lift-off treatment of nanoimprint resin
Gold nanoparticle adhesion and hydrophilicity confirmation
Step 8
Confirming hydrophilicity of hole areas by gold nanoparticle adhesion

* The above is one example process. We propose the optimal process according to device specifications.

Molding Examples
NGS chip well structure

NGS Chip Well Structure (Patterned Flow Cell)

Well structure for DNA sequencer chips used in next-generation sequencers (NGS).

PMF porous membrane film

PMF(Porous Membrane Film)

The world’s first nanoimprint through-hole film. It supports a wide range of bio applications such as OOC.


Foundry Consultation for Bio Devices

We will propose a solution tailored to your specifications and production scale. Please feel free to contact us.

Contact Us